Andreia Almeida, PhD

Caution! Distinct glycosylation of SARS-CoV-2 RBD shed new light in its binding characteristics.

Caution! Distinct glycosylation of SARS-CoV-2 RBD shed new light in its binding characteristics.

Globally, SARS-CoV-2 coronavirus has infected over 100 million individuals, caused millions of deaths, and dramatically impacted everyday life. The coronavirus is an enveloped RNA virus whose membrane spike glycoprotein – …

Caution! Distinct glycosylation of SARS-CoV-2 RBD shed new light in its binding characteristics. Read More »

Hitching timsTOF to the proteogenomics wagon takes autoantibody clonal analysis to the next level of sensitivity.

Hitching timsTOF to the proteogenomics wagon takes autoantibody clonal analysis to the next level of sensitivity.

Pulmonary alveolar proteinosis (PAP) is a disorder causing accumulation of surfactant material in the lung. The autoimmune variant (aPAP) predominates, thought to be caused by elevated levels of granulocyte-macrophage colony-stimulating …

Hitching timsTOF to the proteogenomics wagon takes autoantibody clonal analysis to the next level of sensitivity. Read More »

The FAScinating truth: Innate immune signalling driven by caspase-8 cleavage of N4BP1.

The FAScinating truth: Innate immune signalling driven by caspase-8 cleavage of N4BP1.

Mutations in FAS play a crucial role in the development of severe immunodeficiency, which is promoted by aberrant T lymphocyte death. In addition to this, mutations in caspase-8 or FADD, …

The FAScinating truth: Innate immune signalling driven by caspase-8 cleavage of N4BP1. Read More »