nanoUHPLC columns | IonOpticks

High-performance packed emitter columns

Emitter column

Nanoflow chromatography that radically improves the results from LC-MS-based proteomics.

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What our customers have to say

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Neal Gould
Neal Gould

Tegmine Therapeutics

The Aurora columns are fantastic. Not only do they perform better than other columns on the market but they're durable and the single nano connection makes setup easy and simplifies troubleshooting. I use them for all my routine peptide and PTM applications.

Assoc. Prof. Nikolai Slavov
Assoc. Prof. Nikolai Slavov

Northeastern University

We obtained better results with IonOpticks...

 

We were able to leverage the very high accuracy of retention times as an additional feature to increase confidence in correct peptide identifications and to reduce confidence in incorrect ones.

Akinori Endo, PhD
Akinori Endo, PhD

Laboratory of Protein Metabolism
Tokyo Metropolitan Institute of Medical Science
Tokyo, Japan

We are very pleased with the performance of the Aurora column that can be applied to most proteomics studies. They allow us to acquire MS data with higher quality and especially improved in-depth proteomics output.

Dr. Alex von Kriegsheim
Dr. Alex von Kriegsheim

Edinburgh Cancer Research UK Centre
Institute of Genetics and Molecular Medicine
University of Edinburgh

We have switched all our instruments from in-house packed 35cm emitters to Aurora columns. Their performance is equal or superior to our in-house packed columns, their spray-stability and durability is exceptional, they are fool-proof to install and last hundreds of runs.

Martin R. Larsen, PhD
Martin R. Larsen, PhD

Protein Research Group, University of Southern Denmark
Odense, Denmark

We have recently started to use the Aurora columns and they significantly outperform any other columns that we have ever used for nano-LC-MSMS, by providing much higher peptide coverage in proteomics and phosphoprotemics.

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Prep. Plug. Play.

Our unique nanoZero® fittings withstand the highest pressure connections.

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Resources

Explore our library of support material and resources to help you get started with Aurora Series columns.

Product brochures and user guides available in English, Japanese and Simplified Chinese.

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Latest news

Read about the latest publications, news, events and product updates from IonOpticks

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See you in Minneapolis! #ASMS2022
See you in Minneapolis! #ASMS2022
PRESS RELEASE: IonOpticks announces OEM partnership with Bruker
PRESS RELEASE: IonOpticks announces OEM partnership with Bruker
plexDIA: sensitive proteomics with simultaneous deep coverage, high throughput, low missing data.
plexDIA: sensitive proteomics with simultaneous deep coverage, high throughput, low missing data.
CDK4/6 inhibitors: critical regulation of T-cell memory fate commitment in tumour microenvironment.
CDK4/6 inhibitors: critical regulation of T-cell memory fate commitment in tumour microenvironment.
Visit us at HUPO ReCONNECT
Visit us at HUPO ReCONNECT
MS3 for TMT, not me! TMTProC- improved MS2 accuracy and sensitivity using complementary ions.
MS3 for TMT, not me! TMTProC- improved MS2 accuracy and sensitivity using complementary ions.
On chip: multiplexed low input TMT-labelled quantitative proteomics with digital microfluidics.
On chip: multiplexed low input TMT-labelled quantitative proteomics with digital microfluidics.
Interactions between SARS-CoV-2 viral proteins and host proteins reveal mechanisms of infection
Interactions between SARS-CoV-2 viral proteins and host proteins reveal mechanisms of infection
Unlock the full potential of your mass spec
Unlock the full potential of your mass spec
‘Til death do us part: conformational change for MLKL, disengagement from RIPK3 in necroptosis.
‘Til death do us part: conformational change for MLKL, disengagement from RIPK3 in necroptosis.
PP2A, CDK9 transcription checkpoint interplay? Check! Targetable tumorigenesis inhibitor? Check!
PP2A, CDK9 transcription checkpoint interplay? Check! Targetable tumorigenesis inhibitor? Check!
Cell surface proteomics reveals major new targets for regulation by MARCH proteins.
Cell surface proteomics reveals major new targets for regulation by MARCH proteins.
Driving apoptosis; MIB2, an E3 ligase protein to the cockpit!
Driving apoptosis; MIB2, an E3 ligase protein to the cockpit!
The truth about aging; proteomic characterisation of young and old mouse hematopoietic stem and progenitor cells.
The truth about aging; proteomic characterisation of young and old mouse hematopoietic stem and progenitor cells.
Caution! Distinct glycosylation of SARS-CoV-2 RBD shed new light in its binding characteristics.
Caution! Distinct glycosylation of SARS-CoV-2 RBD shed new light in its binding characteristics.
Assoc. Prof. Nikolai Slavov talks Single-cell proteomics and the SCoPE2 method
Assoc. Prof. Nikolai Slavov talks Single-cell proteomics and the SCoPE2 method
G4 nucleic acid structures act as extra-chromosomal inhibitors in ISG cancer gene regulation.
G4 nucleic acid structures act as extra-chromosomal inhibitors in ISG cancer gene regulation.
Targeted tyrosine phosphorylation profiling in precision oncology using SureQuant pTyr.
Targeted tyrosine phosphorylation profiling in precision oncology using SureQuant pTyr.
Phosphoproteomics with EasyPhos V2: Shorter workflow. Better sensitivity on limited starting material.
Phosphoproteomics with EasyPhos V2: Shorter workflow. Better sensitivity on limited starting material.
Club bouncer: the ubiquitin system dynamically regulates mitochondrial import at the TOM complex.
Club bouncer: the ubiquitin system dynamically regulates mitochondrial import at the TOM complex.
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Follow Us

Like. Follow. Share.

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@IonOpticks

2022-08-08

Generation 3 nanoZero® now holds pressure >1700 bar and improves ease of use and column life. Check out this quick tip on how to connect the nanoZero® to your UHPLC line.

Learn more in our Help Centre: https://t.co/z4OOy4ahXz
#LCMS #UHPLC #massspec #proteomics https://t.co/JsNglk3xFY
@IonOpticks

2022-08-05

Ever wondered how Aurora Series™ columns interface with Bruker’s CaptiveSpray housing?
Here’s a quick snippet from our recent installation videos to show how our Bruker-compatible products are designed to integrate seamlessly and efficiently.

For more: https://t.co/wKz931DUBl https://t.co/O6L4tJBENY
@IonOpticks

2022-08-03

Have a read of this recent study by Juergen Gindlhuber, Ruth Birner-Gruenberger et al. comparing the effects of harmful single-fatty-acid treatments and well-tolerated fatty acid mixes on the cellular proteome to differentiate between cellular responses.

#Lipotoxicity
@IonOpticks

2022-08-03

2022 is the year of events and product releases. We're still buzzing from ASMS, and maintaining momentum as we head to Europe for #IMSC2022 in a few weeks to show you all what we've been working on. If you haven’t already registered, it’s not too late!
https://t.co/fxv0aIUlmf https://t.co/DaKdZJsKXR
@IonOpticks

2022-08-02

A @NatureBiotech paper from @_JasonDerks and a team in the @SlavovLab introduces a framework called plexDIA that increases the throughput of sensitive #proteomics by simultaneously multiplexing the analysis of peptides and samples.

@slavov_n

❔ Q&A: https://t.co/mrpWMDw62a https://t.co/nxNGHL5gZ5
@IonOpticks

2022-08-01

Find out what makes Generation 3 Aurora Series packed emitter columns the global leader in chromatography for high-end proteomics labs.

Shop now: https://t.co/M6kKQniu5i

#LCMS #UHPLC #massspectrometry https://t.co/nrv0A5Z8GG
@IonOpticks

2022-08-01

We believe that installing #UHPLC columns should be a breeze. That’s why we’ve created videos to walk you through each step of installing your Aurora Series™ column. You can watch the specific installation video for your column in our Help Centre here 👉 https://t.co/z4OOy4ahXz https://t.co/3hIUdphXOH
@IonOpticks

2022-07-30

This morning I was asked 3 times by different colleagues for quantifying post-translational modifications (PTMs) in single cells.

Below is a link to thoughts and data on single-cell PTM analysis that were presented at the @SCP_meeting

https://t.co/J71uSkLhPq https://t.co/JPXjsV0Wud
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