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IN THIS EDITION: Big things are happening at IonOpticks. We’re excited to welcome Erik Verschuuren as our new Global Head of Sales, and Zac Anderson as Business Development Manager for … Continued
IN THIS EDITION 2024 has come to an end, and with it, another huge year for IonOpticks. We know it’s cliché to say, but it’s seriously hard to believe that … Continued
IN THIS EDITION: Dr. Jarrod Sandow, Chief Product Officer at IonOpticks, returned to WEHI (Walter and Eliza Hall Institute of Medical Research) to share his entrepreneurial journey at their Entrepreneurship … Continued
15 May 2026
Rapid photo-crosslinking in living cells reveals protein–nucleic acid dynamics on a timescale of minutes
Estimated Reading Time: 2 minutes
Graphical abstract. From Trendel et al., 2026. “Rapid photo-crosslinking in living cells reveals protein–nucleic acid dynamics on a timescale of minutes.“ Nucleic Acids Research (2026). doi: https://doi.org/10.1093/nar/gkag339; Licensed under the terms of the Creative … Continued
15 May 2026
Preprint: Molecular dissection of protein complexes isolated from sections of human brain
Estimated Reading Time: 2 minutes
Image modified from kjpargeter on Magnific Understanding how glutamate receptors are organised in the human brain, and how that organisation changes in disease, has long been limited by the lack … Continued
28 April 2026
Preprint: Pushing the limits of SCP: bacSCP, a proof-of-concept study to investigate heterogeneity of bacteria by single cell proteomics
Estimated Reading Time: 2 minutes
Single cell proteomics (SCP) has advanced significantly for eukaryotic cells, enabling the identification of thousands of proteins per cell. However, bacteria present a far greater technical challenge: they are roughly … Continued
20 April 2026
Preprint: Integrated multi-omics enabled by sequential extraction for comprehensive molecular profiling of small extracellular vesicles
Estimated Reading Time: 1 minute
Image cropped from photoangel on Freepik Small extracellular vesicles (sEVs) are nanoscale, membrane-bound particles secreted by all cell types, carrying protein, lipid, and metabolite cargoes that reflect their cell of … Continued
07 April 2026
Preprint: Multi-omics definition of the sex-specific glycoproteome of murine tissues
Estimated Reading Time: 2 minutes
Image cropped from pikisuperstar on Freepik Biological sex is a well-recognised driver of disease susceptibility, drug response, and immune function, yet its influence on protein glycosylation (a post-translational modification critical … Continued
31 March 2026
Low-resolution FAIMS for increased peptide coverage in low-load and single-cell proteomics
Estimated Reading Time: 2 minutes
Field Asymmetric Ion Mobility Spectrometry (FAIMS) is widely used in proteomics to enhance selectivity and reduce chemical noise, but traditional high-resolution settings limit peptide coverage due to narrow compensation voltage … Continued