News & Publications

Experimental scheme of IFN-γ treatment and bulk preparation of U-2 OS cells in the DIA-ME workflow, followed by protein identification metrics. From Krull et al., 2024. “Enhanced feature matching in … Continued

Through single-cell RNA sequencing of 225,382 individual transcriptomes from 74 donors, Tuddenham et al. investigated microglial heterogeneity across neurodegenerative diseases. The researchers out of the Jager lab identified 12 distinct … Continued

Photo by Freepik Potential therapeutic target in acute myeloid leukemia (AML): Geng et al. explore the development of molecular glue degraders (MGDs) targeting casein kinase 1 alpha (CK1α), a potential … Continued

Image rotated by DC Studio on Freepik Heaton et al. investigated the role of LRRK2 mutations in Crohn’s disease (CD) and Parkinson’s disease (PD), focusing on understanding how the N2081D … Continued

Stratification of mitochondrial disease patients in proteomics data. From Mori et al., 2024. “Quantitative proteomics of patient fibroblasts reveal biomarkers and diagnostic signatures of mitochondrial disease“, JCI Insight. 2024;9(20):e178645. Licensed under … Continued

Photo by Freepik The molecular architecture of the SARS-CoV-2 double-membrane vesicle (DMV) pore complex, a crucial component in coronavirus replication, has been unveiled in a study by Huang et al. … Continued