News & Publications
Explore our latest publications, news and recent newsletters.
17 April 2025
A simplified perchloric acid workflow with neutralization (PCA-N) for democratizing deep plasma proteomics at population scale
Estimated Reading Time: 2 minutes
Image by Freepik Large-scale plasma proteomics studies have been limited by a fundamental trade-off between analytical depth and practical feasibility. While standard undepleted (NEAT) plasma analysis offers simplicity and high … Continued
08 April 2025
Spatially resolved proteomic signatures of atherosclerotic carotid artery disease
Estimated Reading Time: 2 minutes
Image modified from user6702303 on Freepik. Carotid plaque rupture is a major cause of cerebrovascular events, yet predicting which plaques will rupture remains challenging. While severe stenosis was once the … Continued
08 April 2025
Enhanced sensitivity and scalability with a Chip-Tip workflow enables deep single-cell proteomics
Estimated Reading Time: 2 minutes
Workflow and results of Chip-Tip SCP. From Ye et al., 2025. “Enhanced sensitivity and scalability with a Chip-Tip workflow enables deep single-cell proteomics“, Nat Methods 22, 499–509 (2025). https://doi.org/10.1038/s41592-024-02558-2. Licensed under … Continued
02 April 2025
Single Cell Proteomics Reveals Specific Cellular Subtypes in Cardiomyocytes Derived from Human iPSCs and Adult Hearts
Estimated Reading Time: 2 minutes
Graphical abstract. From Ai et al., 2025. “Single Cell Proteomics Reveals Specific Cellular Subtypes in Cardiomyocytes Derived from Human iPSCs and Adult Hearts“, Molecular & Cellular Proteomics, 2025, 100910, ISSN … Continued
02 April 2025
TurboCas: A method for locus-specific labeling of genomic regions and isolating their associated protein interactome
Estimated Reading Time: 2 minutes
Image by vecstock on Freepik Existing methods for studying chromatin-binding proteins have significant limitations. These approaches preclude dynamic mapping of factor activity at specific genomic regions. Cenik et al. developed … Continued
26 March 2025
Stress Granules Underlie Acute Myeloid Leukemia Stem Cell Survival and Stress Adaptation
Estimated Reading Time: 2 minutes
Image modified from starline on Freepik Acute myeloid leukaemia (AML) is an aggressive blood cancer characterised by uncontrolled growth of immature blood cells, with a 5-year survival rate of 23%, … Continued
IN THIS EDITION: Big things are happening at IonOpticks. We’re excited to welcome Erik Verschuuren as our new Global Head of Sales, and Zac Anderson as Business Development Manager for … Continued
IN THIS EDITION 2024 has come to an end, and with it, another huge year for IonOpticks. We know it’s cliché to say, but it’s seriously hard to believe that … Continued
IN THIS EDITION: Dr. Jarrod Sandow, Chief Product Officer at IonOpticks, returned to WEHI (Walter and Eliza Hall Institute of Medical Research) to share his entrepreneurial journey at their Entrepreneurship … Continued