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IonOpticks at #ASMS2025: Our biggest presence yet.
June 1, 2025 @ 8:00 am – June 5, 2025 @ 5:00 pm UTC+10

Thanks for having us, Baltimore.
We’re back home in Melbourne after a sensational ASMS 2025.
Thank you to the American Society for Mass Spectrometry and to the U.S. for once again being great hosts and putting on such an unforgettable event.
The amount of support and interest from the research community in our new releases has been overwhelming. Good thing we had more people at the booth than ever! It never gets tiring hearing about the multitude of ways mass spectrometry is being used to shape the future of research. Just when we think we’ve heard it all, we learn something groundbreaking. To play even a small part in that is an honour.
Although, with over 40 posters and seven oral presentations citing Aurora Series columns, our part is slowly growing. It’s great to be featured in your work. You can see the full list by scrolling down and expanding the ‘Posters’ section.
OUR PRESENCE

Dr. Andreia Almeida, Senior Research and Development Scientist, IonOpticks
Monday, June 2 from 10:30am – 2:30pm
(MP 727) Enhanced proteoform identification in top-down proteomic workflows using packed emitter columns
ABSTRACT
Top-down proteomics has emerged as a powerful analytical approach for characterising intact proteins and their proteoforms offering unique insights into protein structure, post-translational modifications (PTMs), and biological function. Proteoform identification is generally achieved by separation of intact proteins using reversed-phase liquid chromatography (LC) followed by fragmentation and detection on a mass spectrometer. One of the biggest challenges in the field is the inability to identify different proteoforms due to overlapping separation profiles created by limited peak capacity. To address this, we developed a novel packed emitter chromatography column containing a C4 stationary phase. We demonstrate that this column achieves narrow peak widths and sensitive ionisation enabling the efficient separation of complex intact proteins mixtures.
P R E S E N T E R
Dr Andreia Almeida, Senior Research & Development Scientist, IonOpticks
Dr. Andreia Almeida is a dedicated Senior Research and Development Scientist at IonOpticks, with over four years of commitment to pioneering advanced proteomics tools for LC-MS-based research. Her career trajectory is notable for its international span and focus on glycomics and glycoproteomics, reflecting a deep engagement with cutting-edge biomolecular research. Andreia’s expertise is grounded in a solid educational foundation, with a Ph.D. in Biochemistry and Molecular Biology from Griffith University and a Bachelor’s in Biochemistry from Universidade de Aveiro, where she graduated with honors.
Her professional journey includes impactful roles at the prestigious Max Planck Institute of Colloids and Interfaces in Germany and the Instituto Nacional de Saúde Dr. Ricardo Jorge in Portugal, underscoring her proficiency in clinical proteomics. At the Institute for Glycomics, she contributed significantly to a major mass spectrometry facility, showcasing her skill in advanced analytical techniques.
In her current role at IonOpticks, Andreia continues to innovate in the field of chromatography, significantly advancing the capabilities of nano capillary chromatography columns and reinforcing her status as a leading figure in the quest to unlock the secrets of proteomics for health advancements.

Martin Rykær, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen
Monday, June 2 from 08:30am – 08:50am | Hall AB
MOA am: Quantitative Proteomics: Instrumentation and Applications
Modified Orbitrap Astral MS allows for higher scan rates without compromising spectral quality and sensitivity in proteomics

Tim Heymann, Max Planck Institute of Biochemistry
Monday, June 2 from 08:50am – 09:10am | Ballroom IV
MOH am: Challenges in MS Analysis of Complex Mixtures
A Solid Phase Extraction Capture (SPEC) device for ultra-robust and ultra-sensitive proteomics

Timon Geib, McGill University – Lady Davis Institute
Monday, June 2 from 10:10am – 10:30am
MOF am: Biomarkers: Quantitative Analysis (Ballroom I)
SysQuan: Revolutionizing Large-Scale Absolute Quantitative Liver Proteomics with an Affordable Single-Injection Workflow using Stable Isotope-Labeled Mouse

Claudia Ctortecka, Broad Institute of MIT and Harvard
Tuesday, June 3 from 03:10pm – 03:30pm
TOA pm: Data-Independent Acquisition: Acquisition and Multiplexing (Hall AB)
Sensitive detection of cancer neoantigens enabled by user-defined peptide libraries

Larry Rodriguez, Scripps Research
Wednesday, June 4 from 09:50am – 10:10am
WOA am: Single Cell Omics (Hall AB)
Patching Proteomes: A Guide for Effectively Combining Patch Clamp Electrophysiology With Single-Cell Proteomics

Syed Azmal Ali, German Cancer Research Center (DKFZ)
Wednesday, June 4 from 10:10am – 10:30am
WOH am: Cancer Research (Ballroom IV)
Decoding adaptive drug resistance to KRAS-G12C inhibition through nascent and single-cell proteomics

Denys Oliinyk, Max Planck Institute of Biochemistry
Thursday, June 5 from 08:50am – 09:10am
ThOE am: Posttranslational Modifications: Qualitative and Quantitative Analysis (Ballroom II)
Orders of magnitude sensitivity improvement in phosphoproteomics via nanoPhos
FEATURED LITERATURE

Achieve high sensitivity and throughput in low-input proteomics with Aurora Rapid 8×75
We’re pleased to have released our latest application note at ASMS 2025.
These results demonstrate that the Aurora Rapid 8 cm × 75 µm columns, operated at different SPD methods, deliver robust and reproducible performance for low-input proteomics. Across hundreds of runs, the columns maintained stable backpressure, narrow peak widths and high protein and peptide identifications – confirming column suitability for large-scale, high-throughput proteomic applications.
Read the full app note – also available at booth 242.
Are you heading to ASMS 2025 in Baltimore?
Please join us as we close out the conference
at this invite-only cruise on Thursday, June 5.
