CDK4/6 inhibitors: critical regulation of T-cell memory fate commitment in tumour microenvironment.

CDK4/6 inhibitors: critical regulation of T-cell memory fate commitment in tumour microenvironment.

Pharmacologic inhibitors of cyclin-dependent kinases 4 and 6 (CDK4/6) have well-defined tumour-intrinsic cytostatic mechanisms. They are an approved treatment for hormone receptor–positive breast cancer and currently under evaluation in numerous …

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