Peptide-and Protein-Level Combined Strategy for Analyzing Newly Synthesized Proteins by Integrating Tandem Orthogonal Proteolysis with Cleavable Bioorthogonal Tagging
A new study proposes a strategy for analyzing newly synthesized proteins by integrating two different proteomic approaches, tandem orthogonal proteolysis (TOP) and cleavable bioorthogonal tagging (CBOT). This strategy (TOP-CBOT) allows …