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Troubleshooting Guide

We’re here to help.

Whether you’re seeing changes in pressure, retention time shifts, peak shape issues, reduced sensitivity, or unexpected variation in your results, this guide is designed to help you diagnose potential causes and take steps to remedy with confidence.

Follow the prompts below to work through common LC-MS and chromatography challenges, minimise downtime, and get your workflow back on track.

Need additional resources?

Further information is available in our Help Centre.

Browse support articles, instrument compatibility, user guides, and more.

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